What tumor marker is often elevated in non-seminomatous testicular cancer?

Alpha-fetoprotein is a tumor marker that is often elevated in non-seminomatous testicular cancer, particularly in certain subtypes such as embryonal carcinoma and yolk sac tumors. This protein is normally produced by the fetal liver and yolk sac, and its levels can indicate the presence of germ cell tumors in adult males. The elevation of alpha-fetoprotein in the context of testicular cancer assists clinicians in diagnosis, staging, and monitoring treatment response.

In non-seminomatous testicular cancer, other markers such as beta-hCG may also be elevated, particularly in choriocarcinoma or mixed germ cell tumors. However, non-seminomatous tumors specifically are well-characterized by the ability to elevate alpha-fetoprotein. The relevance of measuring these markers lies in their ability to provide insight into tumor type and behavior, which is crucial for effective management and treatment planning.